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Focuses on extreme athlete turned government operative Xander Cage (Vin Diesel) coming out of self-imposed exile and on a collision course with deadly alpha warrior Xiang and his team in a race to recover a sinister and seemingly unstoppable weapon known as Pandora’s Box. Recruiting an all-new group of thrill-seeking cohorts, Xander finds himself enmeshed in a deadly conspiracy that points to collusion at the highest levels of world governments.

As a scientist is near a breakthrough in X-ray vision technology, his funding is cut off. Desperate to show results, he applies eye drops that eventually cause him to lose control over his growing powers.