Lizzie is a Radiator Springs original. She’s a little old lady, but still an active businesswoman who uses her moxie to sell bumper stickers, mud flaps and other Route 66 memorabilia from her curio shop. She’s as feisty as she is brash. Lizzie’s unswerving frankness and offbeat comments keep the townsfolk and tourists on their toes, even though she has no idea what she's just said.
Flo is a sassy, no-nonsense lady with the biggest heart in Radiator Springs. She runs the local diner, Flo's V-8 Café, the only gas station for miles around, where she still serves the "finest fuel in 50 states." Flo is Ramone’s main squeeze. As a touring Motorama girl in the 1950s, Flo was passing through Radiator Springs and when she met Ramone, she was hooked.