Abby (Rosemarie DeWitt), is a sought after massage therapist and a free spirit, while her brother Paul (Josh Pais) thrives on routine and convention, running a flagging dental practice and co-dependently enlisting the assistance of his emotionally stunted daughter Jenny (Ellen Page). Suddenly, transformation touches everyone. Abby develops an uncontrollable aversion to bodily contact, which not only makes her occupation impossible but severely hinders the passionate love life between her and her boyfriend (Scoot McNairy). Meanwhile, rumors of Paul’s “healing touch” begin to miraculously invigorate his practice as well as his life outside the office. As Abby navigates her way through a soul-searching identity crisis, her formerly skeptical brother discovers a whole new side of himself.